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Lifelong Maintenance of Oral Tolerance and Immunity Profiles in Mice Depends on Early Exposure to Antigen
(Blackwell Scientific Publications, 2019)
Use of a Novel Chagas Urine Nanoparticle Test (Chunap) for Diagnosis of Congenital Chagas Disease
(Public Library of Science, 2014)
Detection of congenital T. cruzi transmission is considered one of the pillars of control programs of Chagas disease. Congenital transmission accounts for 25% of new infections with an estimated 15,000 infected infants per ...
Early endosome antigen 1 (EEA1) decreases in macrophages infected with Paracoccidioides brasiliensis
(2013-10-01)
Paracoccidioidomycosis (PCM) is a chronic granulomatous disease caused by the dimorphic fungus Paracoccidioides brasiliensis, endemic in Latin America. P. brasiliensis has been observed in epithelial cells in vivo and in ...
Early endosome antigen 1 (EEA1) decreases in macrophages infected with Paracoccidioides brasiliensis
(2013-10-01)
Paracoccidioidomycosis (PCM) is a chronic granulomatous disease caused by the dimorphic fungus Paracoccidioides brasiliensis, endemic in Latin America. P. brasiliensis has been observed in epithelial cells in vivo and in ...
Evaluation of Toxoplasma gondii recombinant antigens for early diagnosis of congenital toxoplasmosis
(Elsevier Science Inc., 2021-11)
The performance of Toxoplasma rGra8, rMic1, and the chimeric rGra4–Gra7 antigens for early congenital toxoplasmosis (CT) diagnosis was evaluated. Sera from CT patients showed high IgG reactivity to rMic1, rGra8, and ...
Population Screening for Urine Antigens to Detect Asymptomatic Subarachnoid Neurocysticercosis: A Pilot Study in Northern Peru
(American Society of Tropical Medicine and Hygiene, 2020)
Subarachnoid neurocysticercosis (SANCC) is a severe and progressive brain infection with Taenia solium. We performed a pilot study of noninvasive screening for SANCC in two endemic villages in northern Peru using a urine ...
Galectin-8 Enhances T cell Response by Promotion of Antigen Internalization and Processing
(Cell Press, 2020-07)
Galectin-8 (Gal-8) is a mammalian lectin endowed with immunostimulatory ability. In the present work, we demonstrate that Gal-8-glycan interactions on the surface of antigen-presenting cells (APCs) promote antigen binding ...